{"id":4713,"date":"2023-07-28T12:55:42","date_gmt":"2023-07-28T12:55:42","guid":{"rendered":"https:\/\/wapcpharm.org\/journal\/?p=4713"},"modified":"2023-07-31T13:38:01","modified_gmt":"2023-07-31T13:38:01","slug":"west-african-journal-of-pharmacy-2016-27-2-38-52","status":"publish","type":"post","link":"https:\/\/wapcpharm.org\/journal\/west-african-journal-of-pharmacy-2016-27-2-38-52\/","title":{"rendered":"West African Journal of Pharmacy (2016) 27 (2) 38-52"},"content":{"rendered":"\t\t
\n\t\t\t\t\t\t\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t
\n\t\t\t\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t

Pharmacognostic standardization, antioxidant and antimicrobial activities of\u00a0<\/b>Erythrophleum suaveolens (Guill. & Perr.) Brenan and Peltophorum pterocarpum (DC) Backer ex K. Heyne<\/b>, Mubo A. Sonibare , Gavi A. Eseruoma, Bukola M. Omojuyigbe, Ibukun O. Ayoola, Adedapo A. Adeniran<\/b><\/p>

\u00a0<\/b><\/p>

1Department of Pharmacognosy, Faculty of Pharmacy, University of Ibadan, Nigeria<\/span><\/p>

\u00a0<\/p>

Corresponding author: Mubo Sonibare<\/p>

E-mail: sonibaredeola@yahoo.com Phone: +234(0)8134901273<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

\n\t\t\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t
\n\t\t\t\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t

ABSTRACT<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t
\n\t\t\t\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t

Background:<\/b> The plants Erythrophleum suaveolens (Guill. & Perr.) Brenan and Peltophorum pterocarpum (DC)\u00a0Backer ex K. Heyne from the family Fabaceae have been used traditionally as emetic and purgative and as\u00a0<\/span>medicines for dysentry, insomnia, skin diseases, constipation.<\/span><\/p>

Objectives:<\/b> The objective of the present study was to establish the pharmacognostic standards of\u00a0Erythrophleum suaveolens and Peltophorum pterocarpum and to study the antioxidant and antimicrobial\u00a0<\/span>activities of the two plants.<\/span><\/p>

Methods:<\/b> Microscopic, phytochemical and physicochemical evaluations were performed on the leaf samples of\u00a0the plants using standard procedures. Leaf extracts were evaluated for total phenolic content using Folin-<\/span>ciocalteu reagent; in vitro antioxidant activity using DPPH assay, while antimicrobial activity was assessed using\u00a0<\/span>the agar diffusion method.<\/span><\/p>

Results: <\/b>Foliar micro-morphological studies on the plants revealed sharp generic variations in sizes and types of\u00a0stomata, shapes of epidermal cells on the adaxial and abaxial surfaces, sizes and types of trichomes. The\u00a0<\/span>physico-chemical results obtained are within the standard limits. Methanol extract of P. pterocarpum had the\u00a0<\/span>highest phenolic content (62.0\u00b11.23 mg GAE\/g) and the highest antioxidant activity as revealed by its low IC50\u00a0<\/span>value of 21.57\u00b10.62 \u03bcg\/mL. The antimicrobial study revealed that the extracts exhibited diverse activities\u00a0<\/span>against different microorganisms with zones of inhibition ranging from 2.0 to 15.0 mm. The MIC of the extracts r<\/span>anged from 0 .78 to 3.125 mg\/mL and MBC\/MFC from 1.56 to 6.25 mg\/mL for sensitive organisms at the tested\u00a0<\/span>concentrations.<\/span><\/p>

Conclusion:<\/b> The results provide the parameters for the standardization of the plants and also justify their\u00a0ethnomedicinal uses.<\/span><\/p>

Keywords:<\/b> Peltophorum pterocarpum, Erythrophleum suaveolens, standardization, antioxidant, antimicrobial<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

\n\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\tDownload <\/span>\n\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

Pharmacognostic standardization, antioxidant and antimicrobial activities of\u00a0Erythrophleum suaveolens (Guill. & Perr.) Brenan and Peltophorum pterocarpum (DC) Backer ex K. Heyne, Mubo A. Sonibare , Gavi A. Eseruoma, Bukola M. Omojuyigbe, Ibukun O. Ayoola, Adedapo A. Adeniran \u00a0 1Department of Pharmacognosy, Faculty of Pharmacy, University of Ibadan, Nigeria \u00a0 Corresponding author: Mubo Sonibare E-mail: sonibaredeola@yahoo.com Phone: […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[225],"tags":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/posts\/4713"}],"collection":[{"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/comments?post=4713"}],"version-history":[{"count":4,"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/posts\/4713\/revisions"}],"predecessor-version":[{"id":4719,"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/posts\/4713\/revisions\/4719"}],"wp:attachment":[{"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/media?parent=4713"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/categories?post=4713"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/tags?post=4713"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}