{"id":4924,"date":"2023-07-29T15:05:19","date_gmt":"2023-07-29T15:05:19","guid":{"rendered":"https:\/\/wapcpharm.org\/journal\/?p=4924"},"modified":"2023-08-03T15:09:27","modified_gmt":"2023-08-03T15:09:27","slug":"west-african-journal-of-pharmacy-2015-26-2-66-74","status":"publish","type":"post","link":"https:\/\/wapcpharm.org\/journal\/west-african-journal-of-pharmacy-2015-26-2-66-74\/","title":{"rendered":"West African Journal of Pharmacy (2015) 26 (2) 66-74"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"4924\" class=\"elementor elementor-4924\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-a30f05f elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"a30f05f\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-14694e41\" data-id=\"14694e41\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1177e0d8 elementor-widget elementor-widget-text-editor\" data-id=\"1177e0d8\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p style=\"text-align: center;\"><b>Estimation of total carotenoids and free radical scavenging activity of selected vegetables<\/b><\/p><p style=\"text-align: center;\">\u00a0<\/p><p style=\"text-align: center;\">Joseph O. Oiseoghaede and Olukemi A. Odukoya<\/p><p style=\"text-align: center;\">\u00a0<\/p><p style=\"text-align: center;\">1<span style=\"font-size: 19px; color: var( --e-global-color-text );\">Department of Pharmacognosy, Faculty of Pharmacy, University of Lagos.<\/span><\/p><p style=\"text-align: center;\">College of Medicine Campus, Idi-Araba, Lagos, Nigeria.<\/p><p style=\"text-align: center;\">\u00a0<\/p><p style=\"text-align: center;\">Corresponding author: Joseph O. Oiseoghaede<\/p><p style=\"text-align: center;\">E-mail: joseph.oise14@gmail.com Phone: +234 8098253426<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-294f84e5 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"294f84e5\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-3adcb45d\" data-id=\"3adcb45d\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-295312e6 elementor-widget elementor-widget-heading\" data-id=\"295312e6\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">ABSTRACT<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-6785dacb elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"6785dacb\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-3963789c\" data-id=\"3963789c\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-193a46b7 elementor-widget elementor-widget-text-editor\" data-id=\"193a46b7\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p style=\"text-align: justify;\"><b>Background: <\/b>Vegetables are known for their rich carotenoid content responsible for their antioxidant&nbsp;<span style=\"font-size: 19px; color: var( --e-global-color-text );\">properties.<\/span><\/p><p style=\"text-align: justify;\"><b>Objectives:<\/b> This study sought to estimate the total carotenoid content (TCC) in four edible Nigerian vegetables,&nbsp;<span style=\"font-size: 19px; color: var( --e-global-color-text );\">compare their free radical scavenging activity (FRSA) and relate their TCC to their respective FRSA.<\/span><\/p><p style=\"text-align: justify;\"><b>Methods:<\/b> The method employed for extraction involved homogenization with ethanol using a blender.&nbsp;<span style=\"font-size: 19px; color: var( --e-global-color-text );\">Estimation of the TCC was obtained by an equation derived from their Chlorophyll A and B contents from reading&nbsp;<\/span><span style=\"font-size: 19px; color: var( --e-global-color-text );\">absorbances of homogenates at 470nm, 649nm and 665nm. FRSA of ethanolic homogenates on 2,2-diphenyl-1-<\/span><span style=\"font-size: 19px; color: var( --e-global-color-text );\">picrylhydrazyl (DPPH) by decreased absorbance of 1mM DPPH on adding extracts was read at 517nm. The FRSA&nbsp;<\/span><span style=\"font-size: 19px; color: var( --e-global-color-text );\">obtained by 0.2-1% concentrations done in triplicates was compared statistically (ANOVA Test, p&lt;0.01). Mean&nbsp;<\/span><span style=\"font-size: 19px; color: var( --e-global-color-text );\">Inhibitory concentration (IC ) value was obtained graphically via percentage inhibition\/concentration curve. 50<\/span><\/p><p style=\"text-align: justify;\"><b>Results:<\/b> Capsicum annum had the highest TCC compared to the other vegetables. Carica papaya leaves&nbsp;<span style=\"font-size: 19px; color: var( --e-global-color-text );\">exhibited a superior FRSA compared to other plants (p&lt;0.0001). Results showed that there may be a direct&nbsp;<\/span><span style=\"font-size: 19px; color: var( --e-global-color-text );\">relationship between TCC and FRSA. However, Carica papaya which had the highest FRSA did not show a high&nbsp;<\/span><span style=\"font-size: 19px; color: var( --e-global-color-text );\">TCC. Hence, Carica papaya may possess other phytochemicals other than carotenoids responsible for its high&nbsp;<\/span><span style=\"font-size: 19px; color: var( --e-global-color-text );\">FRSA.<\/span><\/p><p style=\"text-align: justify;\"><b>Conclusion: <\/b>This study shows that Carica papaya leaves had a high FRSA and antioxidant capacity due to the&nbsp;<span style=\"font-size: 19px; color: var( --e-global-color-text );\">presence of carotenoids and other beneficial phytochemicals. This evidence supports the fact that it can be&nbsp;<\/span><span style=\"font-size: 19px; color: var( --e-global-color-text );\">included into our diet as Africans.<\/span><\/p><p style=\"text-align: justify;\"><b>Keywords:<\/b> Antioxidant, total carotenoids, free radical scavenging activity, pawpaw.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3586f6e0 elementor-align-right elementor-widget elementor-widget-button\" data-id=\"3586f6e0\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/wapcpharm.org\/journal\/wp-content\/uploads\/2023\/08\/Chapter-6-2.pdf\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-text\">Download <\/span>\n\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Estimation of total carotenoids and free radical scavenging activity of selected vegetables \u00a0 Joseph O. Oiseoghaede and Olukemi A. Odukoya \u00a0 1Department of Pharmacognosy, Faculty of Pharmacy, University of Lagos. College of Medicine Campus, Idi-Araba, Lagos, Nigeria. \u00a0 Corresponding author: Joseph O. Oiseoghaede E-mail: joseph.oise14@gmail.com Phone: +234 8098253426 ABSTRACT Background: Vegetables are known for their [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[224],"tags":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/posts\/4924"}],"collection":[{"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/comments?post=4924"}],"version-history":[{"count":4,"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/posts\/4924\/revisions"}],"predecessor-version":[{"id":4930,"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/posts\/4924\/revisions\/4930"}],"wp:attachment":[{"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/media?parent=4924"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/categories?post=4924"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/tags?post=4924"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}