{"id":5112,"date":"2023-08-04T16:18:45","date_gmt":"2023-08-04T16:18:45","guid":{"rendered":"https:\/\/wapcpharm.org\/journal\/?p=5112"},"modified":"2023-08-05T16:23:51","modified_gmt":"2023-08-05T16:23:51","slug":"west-african-journal-of-pharmacy-2014-25-2-10-20","status":"publish","type":"post","link":"https:\/\/wapcpharm.org\/journal\/west-african-journal-of-pharmacy-2014-25-2-10-20\/","title":{"rendered":"West African Journal of Pharmacy (2014) 25 (2) 10-20"},"content":{"rendered":"\t\t
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Lead Toxicity in Spray Painters: An Intervention with Protective\u00a0\u00a0<\/b>Devices and KPT-4 Herbal (A Preliminary Study)<\/b><\/p>

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Hosea A. Iliya , Kakjing D. Falang , Noel N. Wannang , Dauda A. Dangiwa,\u00a0Kennedy I. Amagon and Bala D. Ntuhun<\/span><\/p>

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1\u00a0Department of Pharmacology, Faculty of Pharmaceutical Sciences, University of Jos, Jos, Nigeria<\/span><\/p>

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2\u00a0Department of Clinical Pharmacy and Pharmacy Practice, Faculty of\u00a0<\/span>Pharmaceutical Sciences, University of Jos, Jos, Nigeria<\/span><\/p>

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3\u00a0Department of Chemical Pathology, University Teaching Hospital, Jos, Nigeria<\/span><\/p>

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Corresponding Author: Hosea A. Iliya<\/p>

E mail: hoseaazi@yahoo.com Phone: +2348033119599<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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ABSTRACT<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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Background<\/b>: Paint and petrol handled by painters have been reported to contain lead which might enter their\u00a0body to produce toxicity.<\/span><\/p>

Objectives:<\/b> This study investigated whether spray painting is associated with lead toxicity and whether an\u00a0intervention using protective devices or KPT \u2013 4 herbal can minimize exposure to lead and\/or lead toxicity.<\/span><\/p>

Methods<\/b>: Fifteen spray painters were recruited for the study. Venous blood was collected from each worker\u00a0for analysis of lead using inductively coupled plasma – optical emission spectrophotometer and for analysis of\u00a0<\/span>packed cells volume (PCV), haemoglobin, uric acid, phosphate, bilirubin, calcium, urea, creatinine, sodium,\u00a0<\/span>potassium, chloride, cholesterol, albumin, total protein, alkaline phosphatase (ALP), aspartate\u00a0<\/span>aminotranferase (AST) and alanine transaminase (ALT). This was followed by an interventional study to\u00a0<\/span>determine whether 6 months intervention with protective devices or KPT \u2013 4 is associated with decreased\u00a0<\/span>blood lead levels and\/or lead toxicity.<\/span><\/p>

Results:<\/b> Blood lead levels were significantly higher (P = 0.004, 485.56 verse 345.75 \u03bcg\/L) in spray painters\u00a0than control group. PCV, haemoglobin and ALP were significantly decreased (35.67, 12.35, 58.47 verse\u00a0<\/span>43.13%, 14.58 g\/dl, 81.40 iu\/L respectively) while uric acid, phosphate, AST and ALT were significantly\u00a0<\/span>elevated (349.27, 1.64, 19.47, 15.60 verse 230.13 \u03bcmol\/L, 1.09 mmol\/L, 9.20 iu\/L, 6.40 iu\/L respectively) in\u00a0<\/span>exposed than unexposed workers. Intervention in spray painters with protective devices or KPT \u2013 4\u00a0<\/span>significantly reduced blood lead levels and lead toxicity.<\/span><\/p>

Conclusion:<\/b> Painters are exposed to lead which may compromise haematological, hepatic and renal\u00a0functions but can be reverted on intervention using protective devices or KPT \u2013 4.<\/span><\/p>

Key words:<\/b> Lead toxicity, spray painters, intervention<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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\n\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\tDownload <\/span>\n\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

Lead Toxicity in Spray Painters: An Intervention with Protective\u00a0\u00a0Devices and KPT-4 Herbal (A Preliminary Study) \u00a0 Hosea A. Iliya , Kakjing D. Falang , Noel N. Wannang , Dauda A. Dangiwa,\u00a0Kennedy I. Amagon and Bala D. Ntuhun \u00a0 1\u00a0Department of Pharmacology, Faculty of Pharmaceutical Sciences, University of Jos, Jos, Nigeria \u00a0 2\u00a0Department of Clinical Pharmacy […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[235],"tags":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/posts\/5112"}],"collection":[{"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/comments?post=5112"}],"version-history":[{"count":4,"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/posts\/5112\/revisions"}],"predecessor-version":[{"id":5118,"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/posts\/5112\/revisions\/5118"}],"wp:attachment":[{"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/media?parent=5112"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/categories?post=5112"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/tags?post=5112"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}