{"id":5126,"date":"2023-08-02T16:47:50","date_gmt":"2023-08-02T16:47:50","guid":{"rendered":"https:\/\/wapcpharm.org\/journal\/?p=5126"},"modified":"2023-08-05T16:52:06","modified_gmt":"2023-08-05T16:52:06","slug":"west-african-journal-of-pharmacy-2014-25-2-31-40","status":"publish","type":"post","link":"https:\/\/wapcpharm.org\/journal\/west-african-journal-of-pharmacy-2014-25-2-31-40\/","title":{"rendered":"West African Journal of Pharmacy (2014) 25 (2) 31-40"},"content":{"rendered":"\t\t
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Some chemical characteristics of novel hemicellulosic Gums From seeds of Afzelia africana and Prosopis\u00a0<\/b>africana<\/b><\/p>

\u00a0<\/p>

Emmanuel O. Olorunsola , Partap G. Bhatia , Babajide A. Tytler , Michael U. Adikwu<\/p>

1 Department of Pharmaceutics and Pharmaceutical Technology, University of Uyo, Uyo, Nigeria<\/p>

2 Department of Pharmaceutics and Pharmaceutical Microbiology, Ahmadu Bello University, Zaria, Nigeria<\/p>

3 Department of Pharmaceutics, University of Nigeria, Nsukka, Nigeria.<\/p>

\u00a0<\/p>

*Corresponding Author:<\/p>

EMAIL olorunsolaeo@yahoo.com Phone: +2348035067306.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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ABSTRACT<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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Background: <\/b>Determination of chemical characteristics of a pharmaceutical excipient is important for\u00a0establishing its compatibility with different drugs.<\/span><\/p>

Objective: This study investigates some chemical characteristics of novel hemicellulosic gums extracted from\u00a0seeds of Afzelia africana and Prosopis africana.<\/span><\/p>

Methods: The afzelia gum (AFG), prosopis gum (PRG) and sodium carboxylmethylcellulose (SCMC) were\u00a0subjected to ash value evaluation, pH determination, atomic absorption spectroscopy, fourier transform\u00a0<\/span>infrared analysis and X-ray powder diffraction.<\/span><\/p>

Results: Afzelia seeds gave a yield of 17 % gum while prosopis seeds gave a yield of 18.2 %. There was no\u00a0significant difference in the yield of hemicelluloses from the two seeds. AFG gave a significantly higher ash\u00a0<\/span>value compared to PRG signifying the presence of higher amount of inorganic substances. There was no\u00a0<\/span>significant difference in the pH of their dispersions. The two hemicelluloses contain significantly higher\u00a0<\/span>amount of potassium and magnesium ions compared to SCMC. The three polymers manifested similar X-ray\u00a0<\/span>diffraction patterns showing that they are closely related.<\/span><\/p>

Conclusion: The two hemicellulosic gums can be differentiated from synthetic cellulose derivatives like SCMC\u00a0on the basis of their potassium and magnesium content. However, being cellulose-related, they are all\u00a0<\/span>characterized by similar X-ray diffraction patterns. The type and level of the different metal ions present in the<\/span>gums reflect their compatibility or otherwise with different types of drugs.<\/span><\/p>

Keywords: afzelia gum, chemical characteristics, hemicelluloses, prosopis gum.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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\n\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\tDownload <\/span>\n\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

Some chemical characteristics of novel hemicellulosic Gums From seeds of Afzelia africana and Prosopis\u00a0africana \u00a0 Emmanuel O. Olorunsola , Partap G. Bhatia , Babajide A. Tytler , Michael U. Adikwu 1 Department of Pharmaceutics and Pharmaceutical Technology, University of Uyo, Uyo, Nigeria 2 Department of Pharmaceutics and Pharmaceutical Microbiology, Ahmadu Bello University, Zaria, Nigeria 3 […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[235],"tags":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/posts\/5126"}],"collection":[{"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/comments?post=5126"}],"version-history":[{"count":4,"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/posts\/5126\/revisions"}],"predecessor-version":[{"id":5132,"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/posts\/5126\/revisions\/5132"}],"wp:attachment":[{"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/media?parent=5126"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/categories?post=5126"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/tags?post=5126"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}