{"id":5272,"date":"2023-08-02T08:00:20","date_gmt":"2023-08-02T08:00:20","guid":{"rendered":"https:\/\/wapcpharm.org\/journal\/?p=5272"},"modified":"2023-08-08T08:06:46","modified_gmt":"2023-08-08T08:06:46","slug":"west-african-journal-of-pharmacy-2012-23-2-40-50","status":"publish","type":"post","link":"https:\/\/wapcpharm.org\/journal\/west-african-journal-of-pharmacy-2012-23-2-40-50\/","title":{"rendered":"West African Journal of Pharmacy (2012) 23 (2) 40 \u2013 50"},"content":{"rendered":"\t\t
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Effects of Acetylation on the Micromeritics of Yam (Dioscorea sp.)\u00a0<\/b>Starch Powder for Pharmaceutical Application<\/b><\/p>

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Alexia C. Harvey , Amusa S. Adebayo, Andrew O. Wheatley,\u00a0Helen N. Asemota , Cliff K. Riley<\/span><\/p>

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1\u00a0Department of Basic Medical Sciences (Biochemistry), University of the West Indies, Mona Campus,\u00a0<\/span>Kingston 7, Jamaica.<\/span><\/p>

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2\u00a0Department of Biopharmaceutical Sciences, College of Pharmacy, Roosevelt University, Schaumburg, IL 60192<\/span><\/p>

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3\u00a0College of Health Sciences, University of Technology, Jamaica.<\/span><\/p>

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Corresponding Author: Amusa S. Adebayo<\/p>

Email: aadebayo02@roosevelt.edu, Phone: 847-330-4548<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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ABSTRACT<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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Background: <\/b>Starch constituents contributes to its intrinsic and binding properties. Native starch is insoluble in cold water and tends to undergo uncontrolled viscosity (pasting) on application of heat. These <\/span>inherent weaknesses of native starch powders have been modified through thermal and chemical <\/span>processes such as acetylation, acylation, carboxymethylation, oxidation and pregelatinization<\/span><\/p>

Objectives:<\/b> Effect of acetylation on micromeritics of starch from five yam varieties grown in Jamaica was investigated.<\/span><\/p>

Methods:<\/b> Native starch pre-treated with pyridine was reacted with acetic anhydride and acetylation process was monitored with Fourier Transformed Infrared Spectroscopy (FTIR) and by volumetric titration <\/span>of the hydrolyzed starch acetate. Particle size and size distribution were determined microscopically and <\/span>the mean diameter (dp) was treated to the Edmundson’s equation to obtain various derived size <\/span>parameters.<\/span><\/p>

Results:<\/b> Yield of starch acetates ranged from 93.18 to 113.96% of different native starch varieties. Presence of a distinct peak in the ester range (1750-1735 cm-1) indicates acetylation and the degree of <\/span>substitution was between 0.15\u00b10.01 and 0.33\u00b10.03. Starches from different yam varieties differ <\/span>significantly (p<0.05) in specific surface area, particle mass, density, together with particle shape. These <\/span>parameters could be used to distinguish starch acetates of different botanic sources. Correlation of degree <\/span>of substitution with the amylose content and the specific surface area suggests that the amylose content <\/span>contributed more significantly to the degree of the substitution than the effective surface area of the <\/span>starch.<\/span><\/p>

Conclusion:<\/b> Acetylation resulted in significant changes of the micromeritics of varieties of native yam (Dioscorea sp.) starch powders and may impact formulation compressibility, fluidity, mixing and <\/span>homogeneity.<\/span><\/p>

Key words<\/b>: acetylation, yam starch varieties, amylose content, micromeritics.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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\n\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\tDownload <\/span>\n\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

Effects of Acetylation on the Micromeritics of Yam (Dioscorea sp.)\u00a0Starch Powder for Pharmaceutical Application \u00a0 Alexia C. Harvey , Amusa S. Adebayo, Andrew O. Wheatley,\u00a0Helen N. Asemota , Cliff K. Riley \u00a0 1\u00a0Department of Basic Medical Sciences (Biochemistry), University of the West Indies, Mona Campus,\u00a0Kingston 7, Jamaica. \u00a0 2\u00a0Department of Biopharmaceutical Sciences, College of Pharmacy, […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[237],"tags":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/posts\/5272"}],"collection":[{"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/comments?post=5272"}],"version-history":[{"count":7,"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/posts\/5272\/revisions"}],"predecessor-version":[{"id":5281,"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/posts\/5272\/revisions\/5281"}],"wp:attachment":[{"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/media?parent=5272"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/categories?post=5272"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/tags?post=5272"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}