{"id":5289,"date":"2023-07-31T08:28:47","date_gmt":"2023-07-31T08:28:47","guid":{"rendered":"https:\/\/wapcpharm.org\/journal\/?p=5289"},"modified":"2023-08-08T08:32:57","modified_gmt":"2023-08-08T08:32:57","slug":"west-african-journal-of-pharmacy-2012-23-2-58-64","status":"publish","type":"post","link":"https:\/\/wapcpharm.org\/journal\/west-african-journal-of-pharmacy-2012-23-2-58-64\/","title":{"rendered":"West African Journal of Pharmacy (2012) 23 (2) 58 \u2013 64"},"content":{"rendered":"\t\t
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Drug Utilization Review of Anti-Diabetic Medications and Therapeutic\u00a0<\/b>outcome in type 2 Diabetes in a Tertiary Hospital in Northern Nigeria<\/b><\/p>

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Comfort O. Olurishe , Steven S. Gyang , Temidayo O. Olurishe , and Titus T. Shekarau<\/p>

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Pharmacy Department, Ahmadu Bello University Teaching Hospital, Shika-Nigeria<\/p>

Department of Clinical Pharmacy, University of Jos, Jos-Nigeria<\/span><\/p>

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Department of Pharmacology & Therapeutics, Ahmadu Bello University, Zaria-Nigeria<\/span><\/p>

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Corresponding Author: Comfort O. Olurishe<\/p>

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e-mail: comfortolurishe@yahoo.com Telephone : +234 802 355 0257<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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ABSTRACT<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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Background:<\/b> Attainment of therapeutic goals in Type 2 Diabetes Mellitus (T2DM) necessitates the rational use of drugs, given the wide options available and the presence of co-morbid diseases.<\/span><\/p>

Objectives:<\/b> To evaluate the drug utilization parameters and short- term outcome of pharmacotherapy in T2DM patients attending a tertiary hospital in Northern Nigeria.<\/span><\/p>

Methods:<\/b> Data was obtained from the folders of outpatients that attended clinic between June 2010 and June 2011 using a structured proforma and analyzed with descriptive statistics and chi square.<\/span><\/p>

Results:<\/b> The mean number of drugs per prescription was 5.29 \u00b1 0.09, while drugs prescribed from the Essential Drug List were 48.1%. Generic, proprietary prescriptions and fixed dose combinations were 66.72%, 33.27% and <\/span>5.91% respectively. The number of encounters with an injection and an antibiotic, were 18(16.38%) and 19 <\/span>(17.27%) respectively. There was a therapy change in 71.9%, whereas 29.1% had a same drug same dose <\/span>prescription. Metformin-glibenclamide therapy was most utilized (53.27%). There was no statistically significant <\/span>difference between the outcome of therapy in patients with initial poor glycaemic control and those with <\/span>optimum glycaemic control. Hypertension was the commonest co-morbid disease (86.1%) with angiotensin <\/span>converting enzyme inhibitors being most prescribed (72.52%) antihypertensive drugs.<\/span><\/p>

Conclusion:<\/b> Utilization of anti-diabetic agents was rational. However outcome of therapy in patients studied could still be improved by close monitoring of patient factors that may affect efficacy and encouraging patients’ <\/span>adherence.<\/span><\/p>

Key words:<\/b> Drug utilization, Type 2 diabetes mellitus, Metformin-glibenclamide therapy<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Drug Utilization Review of Anti-Diabetic Medications and Therapeutic\u00a0outcome in type 2 Diabetes in a Tertiary Hospital in Northern Nigeria \u00a0 Comfort O. Olurishe , Steven S. Gyang , Temidayo O. Olurishe , and Titus T. Shekarau \u00a0 Pharmacy Department, Ahmadu Bello University Teaching Hospital, Shika-Nigeria Department of Clinical Pharmacy, University of Jos, Jos-Nigeria \u00a0 Department […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[237],"tags":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/posts\/5289"}],"collection":[{"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/comments?post=5289"}],"version-history":[{"count":4,"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/posts\/5289\/revisions"}],"predecessor-version":[{"id":5295,"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/posts\/5289\/revisions\/5295"}],"wp:attachment":[{"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/media?parent=5289"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/categories?post=5289"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wapcpharm.org\/journal\/wp-json\/wp\/v2\/tags?post=5289"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}